Mitochondrial dysfunction and immune microenvironment in gestational diabetes mellitus: insights from bioinformatics analysis and experimental validation
These findings emphasize the critical impact of mitochondrial dysfunction on the pro-inflammatory reprogramming of the placental immune microenvironment in GDM, providing potential targets for anti-inflammatory and immunometabolic interventions.
Authors
- Qin Gao (ORCID: https://orcid.org/0000-0002-5976-8749)
- Aimin Jiang
- Rui Zhao
- Tingting Chai
Institutions
- Academy of Medical Sciences (GB)
- Jinan Maternity And Care Hospital (CN)
- Shandong Tumor Hospital (CN)
- Shandong Provincial QianFoShan Hospital (CN)
- Shandong Maternal and Child Health Hospital (CN)
- Shandong First Medical University (CN)
- Jining Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-26
- DOI
- https://doi.org/10.3389/fimmu.2026.1771616
- Primary Topic
- Gestational Diabetes Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00