Cannabinoid Hyperemesis Syndrome in Adolescents

Cannabinoid hyperemesis syndrome (CHS), a recurring vomiting disorder triggered by long-term, frequent cannabis use, remains underdiagnosed and often leads to unnecessary diagnostic evaluations, increased health care utilization, and mental health burden. We present a large case series of CHS in pediatrics that includes data on treatment efficacy, health care utilization, and comorbidities.