The length of negative proximal resection margin does not significantly influence on the prognosis of Siewert type II adenocarcinoma of esophagogastric junction with or without neoadjuvant chemotherapy

A positive status of PRM appears to be associated with adverse survival outcomes of patients with locally advanced Siewert type II AEG after surgery. However, for patients with negative status, the length of the PRM does not influence survival, regardless of whether they undergo surgical resection alone or NAC followed by surgery.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-02-26
DOI
https://doi.org/10.3389/fonc.2026.1779576
Primary Topic
Esophageal Cancer Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

The length of negative proximal resection margin does not significantly influence on the prognosis of Siewert type II adenocarcinoma of esophagogastric junction with or without neoadjuvant chemotherapy

M X Liu, Lei Chen, Jiadi Xing, Chenghai Zhang et al.
Frontiers in Oncology
Esophageal Cancer Research and Treatment
article

The length of negative proximal resection margin does not significantly influence on the prognosis of Siewert type II adenocarcinoma of esophagogastric junction with or without neoadjuvant chemotherapy

M X Liu, Lei Chen, Jiadi Xing, Chenghai Zhang, Hong Yang, Fei Tan, Kai Xu, Zhendan Yao, Ming Cui
article en

Abstract

A positive status of PRM appears to be associated with adverse survival outcomes of patients with locally advanced Siewert type II AEG after surgery. However, for patients with negative status, the length of the PRM does not influence survival, regardless of whether they undergo surgical resection alone or NAC followed by surgery.

Frontiers in OncologyVol. 16
Peking University (CN), Peking University Cancer Hospital (CN), Ministry of Education (ET)
National Natural Science Foundation of China, Peking University
Good health and well-being
Openalex Percentile: Top 42%
Esophageal Cancer Research and Treatment
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