Association between history of fertility problems and pregnancy and birth complications: A longitudinal population‐based cohort study
In this large cohort of women in Australian, initial associations between fertility problems and adverse pregnancy outcomes were attenuated after adjustment for key health and lifestyle factors. The absence of associations in fully adjusted models suggests that previously reported risks may reflect shared underlying maternal characteristics rather than infertility itself and highlights the importance of cautious interpretation of statistical significance in large observational studies.
Authors
- Cathryn A Tully
- Jessica A. Grieger (ORCID: https://orcid.org/0000-0003-1515-948X)
- Allison M. Hodge (ORCID: https://orcid.org/0000-0001-5464-2197)
- Danielle Schoenaker (ORCID: https://orcid.org/0000-0002-7652-990X)
- Leanne Pacella-Ince
Institutions
- The University of Melbourne (AU)
- Cancer Council Victoria (AU)
- Hillrom (Australia) (AU)
- MRC Lifecourse Epidemiology Unit (GB)
- University of Southampton (GB)
- The University of Adelaide (AU)
Publication Details
- Journal
- Acta Obstetricia Et Gynecologica Scandinavica
- Published
- 2026-02-26
- DOI
- https://doi.org/10.1111/aogs.70178
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00