Small-nucleolar RNA host gene3 (SNHG3) and leukemia-associated non-coding IGF1R activator RNA 1 (LUNAR1) correlated with CRC patients’ clinical features: a step-toward ncRNA-precision

SNHG3 and LUNAR1 might be useful non-invasive bio-molecular markers for CRC monitoring. Being correlated with poorer CRC patients' clinical features, SNHG3 and LUNAR1 lncRNAs might constitute potential putative therapeutic targets for CRC, per identified downstream genes or proteins in silico, a step toward ncRNA-based precision medicine.

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Publication Details

Journal
Scientific Reports
Published
2026-02-26
DOI
https://doi.org/10.1038/s41598-026-37432-y
Primary Topic
Cancer-related molecular mechanisms research
Type
article
Field-Weighted Citation Impact
0.00

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article

Small-nucleolar RNA host gene3 (SNHG3) and leukemia-associated non-coding IGF1R activator RNA 1 (LUNAR1) correlated with CRC patients’ clinical features: a step-toward ncRNA-precision

Omnia Emam, Eman F. Wasfey, Nadia M. Hamdy, Sherif Abdel Halim et al.
Scientific Reports
Cancer-related molecular mechanisms research
article

Small-nucleolar RNA host gene3 (SNHG3) and leukemia-associated non-coding IGF1R activator RNA 1 (LUNAR1) correlated with CRC patients’ clinical features: a step-toward ncRNA-precision

Omnia Emam, Eman F. Wasfey, Nadia M. Hamdy, Sherif Abdel Halim, Mostafa Elnakib, Mohamed Yassin
article en

Abstract

SNHG3 and LUNAR1 might be useful non-invasive bio-molecular markers for CRC monitoring. Being correlated with poorer CRC patients' clinical features, SNHG3 and LUNAR1 lncRNAs might constitute potential putative therapeutic targets for CRC, per identified downstream genes or proteins in silico, a step toward ncRNA-based precision medicine.

Scientific ReportsVol. 16(1)
Ain Shams University (EG), Egyptian Government (EG), Military Medical Academy (EG)
Science and Technology Development Fund
No poverty
Openalex Percentile: Top 41%
Cancer-related molecular mechanisms research
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