Acute Urticaria as the Sole Manifestation of Dengue Fever: A Rare Case Report

Urticaria is a very uncommon dermatological manifestation of infection by the dengue virus. It can hinder diagnosis since some of its features overlap with allergic conditions, such as maculopapular and petechial rashes. We present a case of a 32-year-old male, resident of a dengue-endemic area, who presented with an acute onset of generalized pruritic wheals and angioedema in the absence of any systemic symptoms, including fever. Laboratory tests showed leukopenia, thrombocytopenia, and elevated liver enzymes. Dengue serology confirmed primary infection (NS1 antigen and IgM positive). The patient responded to antihistamines and supportive care without complications. This case highlights the need to consider dengue in the differential diagnosis of acute urticaria in endemic areas, even without typical systemic symptoms.

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Publication Details

Journal
Clinical Case Reports
Published
2026-02-23
DOI
https://doi.org/10.1002/ccr3.72182
Primary Topic
Urticaria and Related Conditions
Type
article
Field-Weighted Citation Impact
0.00
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article

Acute Urticaria as the Sole Manifestation of Dengue Fever: A Rare Case Report

Moyen Uddin Pk, Md Osman Goni, M M Khalil, Mst Ayesha Siddika et al.
Clinical Case Reports
Urticaria and Related Conditions
article

Acute Urticaria as the Sole Manifestation of Dengue Fever: A Rare Case Report

Moyen Uddin Pk, Md Osman Goni, M M Khalil, Mst Ayesha Siddika, Mohammad Shahangir Biswas, Md Matiar Rahman, Maksudul Haque
article en

Abstract

Urticaria is a very uncommon dermatological manifestation of infection by the dengue virus. It can hinder diagnosis since some of its features overlap with allergic conditions, such as maculopapular and petechial rashes. We present a case of a 32-year-old male, resident of a dengue-endemic area, who presented with an acute onset of generalized pruritic wheals and angioedema in the absence of any systemic symptoms, including fever. Laboratory tests showed leukopenia, thrombocytopenia, and elevated liver enzymes. Dengue serology confirmed primary infection (NS1 antigen and IgM positive). The patient responded to antihistamines and supportive care without complications. This case highlights the need to consider dengue in the differential diagnosis of acute urticaria in endemic areas, even without typical systemic symptoms.

Clinical Case ReportsVol. 14(3)
National Committee for Quality Assurance (US), Daffodil International University (BD), Bangladesh Academy of Sciences (BD), Primeasia University (BD), University of Rajshahi (BD), University of Science and Technology Chittagong (BD)
Good health and well-being
Openalex Percentile: Top 43%
Urticaria and Related Conditions
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