Assessment of medication-related risks for mortality prediction in Alzheimer's disease

ACB and ADS scores and PIMCog were more strongly associated with mortality than polypharmacy. These findings highlight the combined effect of clinical factors and support systematic medication review targeting anticholinergic drugs in cognitively vulnerable patients.

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Publication Details

Journal
Maturitas
Published
2026-02-26
DOI
https://doi.org/10.1016/j.maturitas.2026.108896
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Assessment of medication-related risks for mortality prediction in Alzheimer's disease

Théodore Decaix, Emmanuel Cognat, Claire Paquet, Agathe Vrillon et al.
Maturitas
Dementia and Cognitive Impairment Research
article

Assessment of medication-related risks for mortality prediction in Alzheimer's disease

Théodore Decaix, Emmanuel Cognat, Claire Paquet, Agathe Vrillon, Jacques Hugon, Karl Götze, Matthieu Lilamand, Julien Dumurgier, Elodie Bouaziz-Amar, François Mouton-Liger
article en

Abstract

ACB and ADS scores and PIMCog were more strongly associated with mortality than polypharmacy. These findings highlight the combined effect of clinical factors and support systematic medication review targeting anticholinergic drugs in cognitively vulnerable patients.

MaturitasVol. 208
Inserm (FR), Délégation Paris 7 (FR), Université Paris Cité (FR), Sorbonne Paris Cité (FR), Assistance Publique – Hôpitaux de Paris (FR), Hôpital Fernand-Widal (FR), Hôpital Lariboisière (FR), Hôpital Bichat-Claude-Bernard (FR)
Good health and well-being
Openalex Percentile: Top 47%
Dementia and Cognitive Impairment Research
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