Role of thalidomide in angiodysplasia-related gastrointestinal bleeding: a systematic review

Thalidomide appears effective in reducing bleeding episodes in angiodysplasia-related GI bleeding. However, heterogeneity in dosing, outcome definitions, and safety reporting highlights the need for larger, standardized trials to clarify optimal treatment strategies and long-term safety.

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Publication Details

Journal
Frontiers in Gastroenterology
Published
2026-02-26
DOI
https://doi.org/10.3389/fgstr.2026.1669563
Primary Topic
Gastrointestinal Bleeding Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Role of thalidomide in angiodysplasia-related gastrointestinal bleeding: a systematic review

Ruqaiya Shahid Raja, Junaid Khan, Aamir Khan, Zubair Ahmed et al.
Frontiers in Gastroenterology
Gastrointestinal Bleeding Diagnosis and Treatment
article

Role of thalidomide in angiodysplasia-related gastrointestinal bleeding: a systematic review

Ruqaiya Shahid Raja, Junaid Khan, Aamir Khan, Zubair Ahmed, Qamar Iqbal, Mahad Shahid Raja, Simona Eng, Amna Yousaf Shah
article en

Abstract

Thalidomide appears effective in reducing bleeding episodes in angiodysplasia-related GI bleeding. However, heterogeneity in dosing, outcome definitions, and safety reporting highlights the need for larger, standardized trials to clarify optimal treatment strategies and long-term safety.

Frontiers in GastroenterologyVol. 5
Peninsula Regional Medical Center (US), Dar Al-Shifa Hospital (PS), Our Lady of Fatima Hospital (US), Peninsula Health (AU), University at Buffalo, State University of New York (US)
Openalex Percentile: Top 40%
Gastrointestinal Bleeding Diagnosis and Treatment
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