Minimal benefit of co-testing over HPV primary screening with cytology triage from resource-limited settings in China

In resource-limited county programmes, HPV primary screening with cytology triage provides the most favourable balance between detecting cervical pre-cancer and limiting unnecessary procedures. These findings support transitioning from routine co-testing to HPV-based screening tailored to local capacity.

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Publication Details

Journal
Communications Medicine
Published
2026-02-26
DOI
https://doi.org/10.1038/s43856-026-01467-z
Primary Topic
Cervical Cancer and HPV Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Minimal benefit of co-testing over HPV primary screening with cytology triage from resource-limited settings in China

Alex Ng, Chen Gao, Rufei Duan, YouLin Qiao et al.
Communications Medicine
Cervical Cancer and HPV Research
article

Minimal benefit of co-testing over HPV primary screening with cytology triage from resource-limited settings in China

Alex Ng, Chen Gao, Rufei Duan, YouLin Qiao, Xinhua Jia, Jingyi Shi, Xi’ao Da, Shuzhen Qi, Cairun Tang, Yuqian Zhao, Fanghui Zhao, Yahong Wang, Ying Yang, Tai Zhang, Zhifang Li
article en

Abstract

In resource-limited county programmes, HPV primary screening with cytology triage provides the most favourable balance between detecting cervical pre-cancer and limiting unnecessary procedures. These findings support transitioning from routine co-testing to HPV-based screening tailored to local capacity.

Communications Medicine
Changzhi Medical College (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Tencent (China) (CN), Kunming Medical University (CN), Peking Union Medical College Hospital (CN), National Cancer Center (US), Sichuan Mianyang 404 Hospital (CN), Yunnan Maternal and Child Health (CN), Jingzhou Maternal and Child Health Hospital (CN), Sichuan Cancer Hospital (CN), Maternal and Child Health Hospital of Sichuan Province (CN), Dali University (CN)
Tencent
Openalex Percentile: Top 42%
Cervical Cancer and HPV Research
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