Peritumoral-to-tumoral apparent diffusion coefficient ratio as a marker of tumor microenvironment activity across breast cancer molecular subtypes
The p/tADC ratio reflects stromal and microenvironmental changes associated with tumor aggressiveness and may serve as a noninvasive imaging biomarker. Its integration into preoperative MRI protocols may facilitate risk stratification and personalized treatment planning.
Authors
- Eda Elverici (ORCID: https://orcid.org/0000-0002-1539-5047)
- Arzu Özsoy (ORCID: https://orcid.org/0000-0002-0367-4794)
- Leman Günbey Karabekmez (ORCID: https://orcid.org/0000-0001-9862-0192)
- Emre Gündoğdu (ORCID: https://orcid.org/0000-0002-6114-4484)
- Seçil Gündoğdu (ORCID: https://orcid.org/0000-0002-6254-3022)
- Muhammed Said Beşler
Institutions
- Ankara University (TR)
- Bilkent University (TR)
- Memorial Ankara Hospital (TR)
- Başkent University Hospital (TR)
- Yüksek İhtisas Üniversitesi (TR)
- Istanbul Medeniyet University (TR)
Publication Details
- Journal
- Diagnostic and Interventional Radiology
- Published
- 2026-02-26
- DOI
- https://doi.org/10.4274/dir.2026.263742
- Primary Topic
- MRI in cancer diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00