Characterization of exceptional responders with long-term PARP inhibitor therapy in recurrent ovarian cancer: an analysis of 23 patients from Charité

ExR-LTs present with heterogenic clinical and genetic characteristics. Clinical management is complex because of a high rate of AE and need of dose reductions at various points in time. Close monitoring for AE, recurrences and secondary malignancies must be carried out throughout the entire time of treatment.

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Publication Details

Journal
Archives of Gynecology and Obstetrics
Published
2026-02-26
DOI
https://doi.org/10.1007/s00404-026-08309-2
Primary Topic
PARP inhibition in cancer therapy
Type
article
Field-Weighted Citation Impact
0.00
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article

Characterization of exceptional responders with long-term PARP inhibitor therapy in recurrent ovarian cancer: an analysis of 23 patients from Charité

Jacek Glajzer, Joanna Baum, Jacek Grabowski, Hannah Woopen et al.
Archives of Gynecology and Obstetrics
PARP inhibition in cancer therapy
article

Characterization of exceptional responders with long-term PARP inhibitor therapy in recurrent ovarian cancer: an analysis of 23 patients from Charité

Jacek Glajzer, Joanna Baum, Jacek Grabowski, Hannah Woopen, Elena Ioana Braicu, Jalid Sehouli
article en

Abstract

ExR-LTs present with heterogenic clinical and genetic characteristics. Clinical management is complex because of a high rate of AE and need of dose reductions at various points in time. Close monitoring for AE, recurrences and secondary malignancies must be carried out throughout the entire time of treatment.

Archives of Gynecology and ObstetricsVol. 313(1)
Humboldt-Universität zu Berlin (DE), Eberspächer (Germany) (DE)
Good health and well-being
Openalex Percentile: Top 40%
PARP inhibition in cancer therapy
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