Ligustroflavone alleviates chronic kidney disease by inhibiting ferroptosis through the GSK3β/NRF2 signaling pathway

In summary, ligustroflavone inhibits ferroptosis in RTECs and confers protection in CKD. These findings suggest that ligustroflavone holds promise as a potential therapeutic agent for CKD.

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Publication Details

Journal
Redox Report
Published
2026-02-25
DOI
https://doi.org/10.1080/13510002.2026.2636421
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Ligustroflavone alleviates chronic kidney disease by inhibiting ferroptosis through the GSK3β/NRF2 signaling pathway

Jiayu Song, Sutianyi Li, Yunwen Yang, Shaofan Wang et al.
Redox Report
Ferroptosis and cancer prognosis
article

Ligustroflavone alleviates chronic kidney disease by inhibiting ferroptosis through the GSK3β/NRF2 signaling pathway

Jiayu Song, Sutianyi Li, Yunwen Yang, Shaofan Wang, Mingyue Chen, Wen Zhang, Yaru Wang
article en

Abstract

In summary, ligustroflavone inhibits ferroptosis in RTECs and confers protection in CKD. These findings suggest that ligustroflavone holds promise as a potential therapeutic agent for CKD.

Redox ReportVol. 31(1)
Nanjing University of Chinese Medicine (CN), Anhui Medical University (CN), Nanjing General Hospital of Nanjing Military Command (CN), Second Affiliated Hospital of Nanjing Medical University (CN), Yangzhou University (CN)
Good health and well-being
Openalex Percentile: Top 42%
Ferroptosis and cancer prognosis
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