The elite controller phenotype
Elite controllers provide critical insights into mechanisms of durable HIV remission and inform cure-oriented research. Improved stratification of EC phenotypes may help identify individuals approaching spontaneous functional cure. Antiretroviral therapy should be individualized, balancing virological stability, immune activation, comorbidities, and patient preference, while ongoing research aims to translate lessons from ECs into scalable HIV cure strategies.
Authors
- Noël Nicolas
- Olivier Lambotte
Institutions
- Inserm (FR)
- Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR)
- Université Paris-Saclay (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- CEA Paris-Saclay (FR)
- Bicêtre Hospital (FR)
Publication Details
- Journal
- Current Opinion in HIV and AIDS
- Published
- 2026-02-26
- DOI
- https://doi.org/10.1097/coh.0000000000001027
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00