Principal component analysis of cytokine signature in COVID-19 and Long COVID

The coordinated interactions within these clusters reveal a complex immunopathology behind LC: clsuter A repsresenting local immune responses, cluster B for neuroinflammatory processes, and cluster C for changes in the blood vessels. The results, however, leave an opening for further investigatoin and interpretation.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-02-26
DOI
https://doi.org/10.3389/fimmu.2026.1717107
Primary Topic
Long-Term Effects of COVID-19
Type
article
Field-Weighted Citation Impact
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article

Principal component analysis of cytokine signature in COVID-19 and Long COVID

Арег А. Тотолян, Zoia R. Korobova
Frontiers in Immunology
Long-Term Effects of COVID-19
article

Principal component analysis of cytokine signature in COVID-19 and Long COVID

Арег А. Тотолян, Zoia R. Korobova
article en

Abstract

The coordinated interactions within these clusters reveal a complex immunopathology behind LC: clsuter A repsresenting local immune responses, cluster B for neuroinflammatory processes, and cluster C for changes in the blood vessels. The results, however, leave an opening for further investigatoin and interpretation.

Frontiers in ImmunologyVol. 17
First Pavlov State Medical University of St. Petersburg (RU), Saint Petersburg Pasteur Institute (RU)
Reduced inequalities
Openalex Percentile: Top 47%
Long-Term Effects of COVID-19
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