Associations of modified triglyceride-glucose indices with risks of dementia subtypes and brain structure: a prospective cohort study

Modified TyG indices show nonlinear, differential associations with AD and VaD risks, and are linked to structural brain alterations. These findings highlight the importance of metabolic health in dementia prevention and brain aging.

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Publication Details

Journal
Frontiers in Neurology
Published
2026-02-26
DOI
https://doi.org/10.3389/fneur.2026.1750736
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Associations of modified triglyceride-glucose indices with risks of dementia subtypes and brain structure: a prospective cohort study

Tianwen Huang, Xiaodong Pan, Hanying Duan, Xiaochun Chen et al.
Frontiers in Neurology
Dementia and Cognitive Impairment Research
article

Associations of modified triglyceride-glucose indices with risks of dementia subtypes and brain structure: a prospective cohort study

Tianwen Huang, Xiaodong Pan, Hanying Duan, Xiaochun Chen, Jiayao Liu
article en

Abstract

Modified TyG indices show nonlinear, differential associations with AD and VaD risks, and are linked to structural brain alterations. These findings highlight the importance of metabolic health in dementia prevention and brain aging.

Frontiers in NeurologyVol. 17
Fujian Medical University (CN)
National Science Foundation, National Natural Science Foundation of China
Openalex Percentile: Top 47%
Dementia and Cognitive Impairment Research
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