Case Report: High-altitude exposure and severe respiratory infection precipitating diabetic ketoacidosis: new-onset ketosis-prone diabetes unmasked by physiological stress
This case highlights DKA precipitated by recent high-altitude exposure and severe polymicrobial pneumonia in the setting of previously unrecognized chronic dysglycemia, consistent with ketosis-prone diabetes. It underscores the diagnostic value of early bronchoscopy with molecular pathogen detection and the need for stewardship-based interpretation of multiplex PCR results in complex metabolic-respiratory presentations.
Authors
- Diana C Briones-Márquez
- Michelle Grunauer (ORCID: https://orcid.org/0000-0002-5821-7603)
- Amado X. Freire (ORCID: https://orcid.org/0000-0001-7500-8291)
- Anahí D Briones-Zamora
- Fabián Alfonso Ortiz-Herbener
- Jaime Benites-Solis
- Patricia Delgado-Cedeño
- Killen H. Briones-Zamora
Institutions
- Pioneer (United States) (US)
- Universidad Espíritu Santo (EC)
- Instituto Universitario Italiano de Rosario (AR)
- Centro de Investigación en Materiales Avanzados (MX)
- Universidad Internacional del Ecuador (EC)
- OMNI Institute (US)
- Instituto Ecuatoriano de Enfermedades Digestivas (EC)
- Universidad San Francisco de Quito (EC)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-02-26
- DOI
- https://doi.org/10.3389/fmed.2026.1762878
- Primary Topic
- Diabetes and associated disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00