Medication adherence and its associated factors among oral pre-exposure prophylaxis (PrEP) users in China: The Real-world E-consumer Cohort of PrEP study

The study found PrEP adherence was low among ED PrEP users who account for the majority of real-world e-consumers in China. Targeted interventions are suggested to prioritize enhancing users' understanding of medication instructions, promoting self-efficacy of maintaining adherence, and alleviating PrEP-related stigma. Additional attention should be given to ED users who have chemsex, insertive anal sex, multiple sexual partners, or a younger age.

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Publication Details

Journal
PLoS Medicine
Published
2026-02-26
DOI
https://doi.org/10.1371/journal.pmed.1004733
Primary Topic
HIV/AIDS Research and Interventions
Type
article
Field-Weighted Citation Impact
0.00
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article

Medication adherence and its associated factors among oral pre-exposure prophylaxis (PrEP) users in China: The Real-world E-consumer Cohort of PrEP study

Yutong Xu, Sitong Luo, Yuhang Zhang, Qingyu Li et al.
PLoS Medicine
HIV/AIDS Research and Interventions
article

Medication adherence and its associated factors among oral pre-exposure prophylaxis (PrEP) users in China: The Real-world E-consumer Cohort of PrEP study

Yutong Xu, Sitong Luo, Yuhang Zhang, Qingyu Li, Siwen Huang, Chunqing Lin, Jiayin Zheng, Jie Xu, Houlin Tang, Jingtao Zhou, Chi Ruan, Huachun Zou, Jiaqi Cheng, Zhiyi Zhao, Min Zhang, Hui Xue
article en

Abstract

The study found PrEP adherence was low among ED PrEP users who account for the majority of real-world e-consumers in China. Targeted interventions are suggested to prioritize enhancing users' understanding of medication instructions, promoting self-efficacy of maintaining adherence, and alleviating PrEP-related stigma. Additional attention should be given to ED users who have chemsex, insertive anal sex, multiple sexual partners, or a younger age.

PLoS MedicineVol. 23(2)
University of California, Los Angeles (US), Fudan University (CN), Digital China Health (China) (CN), Neurobehavioral Systems (US), Vanke (China) (CN), Tsinghua University (CN)
Good health and well-being
Openalex Percentile: Top 42%
HIV/AIDS Research and Interventions
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