A Rare Paratesticular Leiomyosarcoma Presenting as a Painless Scrotal Mass in an Elderly Patient: A Case Report

Leiomyosarcomas (LMS) are malignant tumors originating from smooth muscle and rarely found in the scrotum. LMS has an insidious presentation that is often misdiagnosed as a benign lesion. This report outlines an innocuous case of paratesticular leiomyosarcoma while focusing on the diagnosis and treatment paratesticular LMS. We report the case of an 84-year-old male who presented with a painless left scrotal swelling of 5 days' duration. Imaging and tumor markers suggested a paratesticular mass suspicious for malignancy. Surgical excision revealed a Fédération Nationale des Centres de Lutte Contre le Cancer Grade 2 leiomyosarcoma arising from the scrotal soft tissue, confirmed by positive smooth muscle markers on immunohistochemistry. Postoperative imaging demonstrated no recurrence at 8 months. This case highlights the diagnostic challenge of paratesticular leiomyosarcoma and the importance of surgical resection and careful follow-up for optimal patient outcomes.

Authors

Institutions

Publication Details

Journal
Journal of Investigative Medicine High Impact Case Reports
Published
2026-02-25
DOI
https://doi.org/10.1177/23247096261420891
Primary Topic
Testicular diseases and treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

A Rare Paratesticular Leiomyosarcoma Presenting as a Painless Scrotal Mass in an Elderly Patient: A Case Report

Dominic Collins, A Kandula, Darshan Sangani, Garrett Douglas et al.
Journal of Investigative Medicine High Impact Case Reports
Testicular diseases and treatments
article

A Rare Paratesticular Leiomyosarcoma Presenting as a Painless Scrotal Mass in an Elderly Patient: A Case Report

Dominic Collins, A Kandula, Darshan Sangani, Garrett Douglas, Roger Robertson, Marvin A. Simpkins
article en

Abstract

Leiomyosarcomas (LMS) are malignant tumors originating from smooth muscle and rarely found in the scrotum. LMS has an insidious presentation that is often misdiagnosed as a benign lesion. This report outlines an innocuous case of paratesticular leiomyosarcoma while focusing on the diagnosis and treatment paratesticular LMS. We report the case of an 84-year-old male who presented with a painless left scrotal swelling of 5 days' duration. Imaging and tumor markers suggested a paratesticular mass suspicious for malignancy. Surgical excision revealed a Fédération Nationale des Centres de Lutte Contre le Cancer Grade 2 leiomyosarcoma arising from the scrotal soft tissue, confirmed by positive smooth muscle markers on immunohistochemistry. Postoperative imaging demonstrated no recurrence at 8 months. This case highlights the diagnostic challenge of paratesticular leiomyosarcoma and the importance of surgical resection and careful follow-up for optimal patient outcomes.

Journal of Investigative Medicine High Impact Case ReportsVol. 14
Marshall University (US)
Good health and well-being
Openalex Percentile: Top 42%
Testicular diseases and treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.