Anti-inflammatory and immunomodulatory effects of human induced pluripotent stem cells-derived mesenchymal stem/stromal cells and their extracellular vesicles
XF-iMSCs and their EVs exert anti-inflammatory and immunomodulatory effects in human and mouse cell-based assays and have promising therapeutic applications for autoimmune diseases.
Authors
- Daisuke KAMIYA (ORCID: https://orcid.org/0000-0002-3510-282X)
- Makoto Ikeya (ORCID: https://orcid.org/0000-0002-3930-8032)
- Hirokazu Matsumoto (ORCID: https://orcid.org/0000-0003-1262-0883)
- Yusaku Komoike
- Haruka Sasaki-Ban
- Atsushi Matsuda
Institutions
- Kyoto University (JP)
- Takeda (Japan) (JP)
Publication Details
- Journal
- Regenerative Therapy
- Published
- 2026-02-26
- DOI
- https://doi.org/10.1016/j.reth.2026.101081
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00