Co-culture of mucosal epithelial cells of nasal polyps and pericytes and the expression and regulation of related factors
This study indicates that in the co-culture model of mucosal epithelial cells of NP and pericytes, the stimulated epithelial cells can upregulate the expression of factors such as POSTN, VCAM-1 and CCL-5 in pericytes. There exists a PDGF/PI3K/AKT/NF-κB signaling pathway between mucosal epithelial cells of NP and pericytes.
Authors
- Dongdong Zhu
- Cuida Meng
- Xuewei Zhu
- Na Cui
Publication Details
- Journal
- International Archives of Allergy and Immunology
- Published
- 2026-02-26
- DOI
- https://doi.org/10.1159/000549978
- Primary Topic
- Sinusitis and nasal conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00