Simultaneous synthesis of perfusion and ventilation images from CT using a dual‐decoder residual attention network for lung disease diagnosis

We have developed a dual-decoder residual attention network that enables the simultaneous synthesis of lung perfusion and ventilation images from three-dimensional CT. Preliminary results indicate moderate-to-high structural-wise and functional-wise concordances, and our proposed model demonstrates comparable accuracy when benchmarked against single-decoder models. The synthesized perfusion and ventilation images can potentially be used for precise diagnosis and guiding functional lung avoidance radiotherapy.

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Publication Details

Journal
Journal of Applied Clinical Medical Physics
Published
2026-02-26
DOI
https://doi.org/10.1002/acm2.70498
Primary Topic
Lung Cancer Diagnosis and Treatment
Type
article
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article

Simultaneous synthesis of perfusion and ventilation images from CT using a dual‐decoder residual attention network for lung disease diagnosis

Tianyu Xiong, Ruijie Yang, Meixin Zhao, J. Cai et al.
Journal of Applied Clinical Medical Physics
Lung Cancer Diagnosis and Treatment
article

Simultaneous synthesis of perfusion and ventilation images from CT using a dual‐decoder residual attention network for lung disease diagnosis

Tianyu Xiong, Ruijie Yang, Meixin Zhao, J. Cai, Li-Sheng Geng, Weifang Zhang, Haoze Li, Meng Wang, David Huang, Xi Liu
article en

Abstract

We have developed a dual-decoder residual attention network that enables the simultaneous synthesis of lung perfusion and ventilation images from three-dimensional CT. Preliminary results indicate moderate-to-high structural-wise and functional-wise concordances, and our proposed model demonstrates comparable accuracy when benchmarked against single-decoder models. The synthesized perfusion and ventilation images can potentially be used for precise diagnosis and guiding functional lung avoidance radiotherapy.

Journal of Applied Clinical Medical PhysicsVol. 27(3)
Hong Kong Polytechnic University (HK), Peking University (CN), Peking University Cancer Hospital (CN), Peking University Third Hospital (CN), Duke Kunshan University (CN), Beihang University (CN)
Good health and well-being
Openalex Percentile: Top 42%
Lung Cancer Diagnosis and Treatment
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