Adoptive transfer of ILC2s reveals tumor homing in glioblastoma: a proof-of-concept study
These findings establish a proof-of-concept that adoptively transferred ILC2s can access and localize within glioblastoma <i>in vivo</i>. While not associated with tumor growth inhibition in this study, the results provide foundational insight into innate immune cell trafficking to central nervous system tumors and support further investigation into the immunomodulatory potential of ILC2s in GBM.
Authors
- Nancy L. Young (ORCID: https://orcid.org/0000-0002-1739-3299)
- Evila Lopez Salles
- L. Phillip Wang
- Sahar Emami Naeini (ORCID: https://orcid.org/0000-0003-2907-2414)
- Jack C. Yu
- Bidhan Bhandari
- Babak Baban
- Ali Arbab
Institutions
- Augusta University (US)
- Augusta University Health (US)
- Atlanta Gastroenterology Associates (US)
- National Cancer Center of Georgia (GE)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-02-26
- DOI
- https://doi.org/10.3389/fonc.2026.1776061
- Primary Topic
- IL-33, ST2, and ILC Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Augusta University