Transcriptome-based high-frequency recurrence index predicts frequent recurrence in non-muscle-invasive bladder cancer after Bacillus Calmette-Guérin therapy

HfRI represents a robust, transcriptome-based tool for predicting frequent recurrence in NMIBC patients. The HfRI supports earlier identification of patients at risk of high-frequency recurrence, thereby supporting personalized treatment strategies.

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Publication Details

Journal
BMC Medicine
Published
2026-02-27
DOI
https://doi.org/10.1186/s12916-026-04745-8
Primary Topic
Bladder and Urothelial Cancer Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Transcriptome-based high-frequency recurrence index predicts frequent recurrence in non-muscle-invasive bladder cancer after Bacillus Calmette-Guérin therapy

Seok Joong Yun, WUN-JAE KIM, Seon-Kyu Kim, Jee-Woo Seo et al.
BMC Medicine
Bladder and Urothelial Cancer Treatments
article

Transcriptome-based high-frequency recurrence index predicts frequent recurrence in non-muscle-invasive bladder cancer after Bacillus Calmette-Guérin therapy

Seok Joong Yun, WUN-JAE KIM, Seon-Kyu Kim, Jee-Woo Seo, Seung-Woo Baek, Young Deuk Choi, Otabek Kamarov, Seongmin Moon, Sung-Kwon Moon, Yung Hyun Choi, Seon-Young Kim, Xuan-Mei Piao, Young Joon Byun, Il-San Jeong, Ho Won Kang, Won Tae Kim, Kyeong Kim
article en

Abstract

HfRI represents a robust, transcriptome-based tool for predicting frequent recurrence in NMIBC patients. The HfRI supports earlier identification of patients at risk of high-frequency recurrence, thereby supporting personalized treatment strategies.

BMC Medicine
Chungbuk National University (KR), Yonsei University (KR), Dong-Eui University (KR), Hanil General Hospital (KR), Chungbuk National University Hospital (KR), Dankook University Hospital (KR), Chung-Ang University (KR), Korea Research Institute of Bioscience and Biotechnology (KR), Korea University of Science and Technology (KR)
Openalex Percentile: Top 42%
Bladder and Urothelial Cancer Treatments
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Transcriptome-based high-frequency recurrence index predicts frequent recurrence in non-muscle-invasive bladder cancer after Bacillus Calmette-Guérin therapy — Seok Joong Yun, WUN-JAE KIM, et al. · BMC Medicine (2026) | TGRS Research Map | TGRS