Retinal Vessel Dysfunction in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), the most common inherited cerebral small vessel disease (cSVD), involves NOTCH3-mediated microvascular pathology. As retinal health remains underexplored, serial ultra-widefield fluorescein angiography (UW-FA) was used to characterize dynamic vessel dysfunction.
Authors
- Alon Friedman (ORCID: https://orcid.org/0000-0003-4780-8456)
- Beth A. Kozel (ORCID: https://orcid.org/0000-0002-9757-7118)
- Camilo Toro (ORCID: https://orcid.org/0000-0002-3917-9031)
- M. Boehm
- Tiarnán D L Keenan (ORCID: https://orcid.org/0000-0002-2253-1772)
- Chantal Cousineau-Krieger (ORCID: https://orcid.org/0000-0003-1008-8950)
- Yonatan Serlin (ORCID: https://orcid.org/0000-0001-5216-120X)
- Elisa A. Ferrante (ORCID: https://orcid.org/0000-0002-0352-709X)
- Alessandra Brofferio
- Lyna Kamintsky (ORCID: https://orcid.org/0000-0001-6776-0969)
- Edmond J. FitzGibbon (ORCID: https://orcid.org/0000-0001-6855-7540)
- Colyn Munn
- Sherrell Apugo
- Richard W. J. Lee
- M. Luisa Iruela-Arispe
- M. Teresa Magone
Institutions
- Northwestern University (US)
- Dalhousie University (CA)
- National Institutes of Health (US)
- Office of the Director (US)
- National Heart, Lung, and Blood Institute (US)
- National Eye Institute (US)
Publication Details
- Journal
- Neurology Open Access
- Published
- 2026-02-26
- DOI
- https://doi.org/10.1212/wn9.0000000000000069
- Primary Topic
- Cerebrovascular and genetic disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00