Logarithmically transformed lactate-to-hemoglobin ratio demonstrates a threshold effect on 28-day mortality in sepsis: Analysis of the MIMIC-IV database

Ln_LHR may represent a promising, readily available prognostic biomarker for sepsis mortality risk stratification, with a clinically meaningful threshold effect. This composite marker integrates critical pathophysiological information and may enhance risk assessment and guide clinical decision-making in sepsis management.

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Publication Details

Journal
PLoS ONE
Published
2026-02-26
DOI
https://doi.org/10.1371/journal.pone.0342994
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Logarithmically transformed lactate-to-hemoglobin ratio demonstrates a threshold effect on 28-day mortality in sepsis: Analysis of the MIMIC-IV database

Shirong Lin, Xiuqin Zheng, Hongping Chen, Da Ke et al.
PLoS ONE
Sepsis Diagnosis and Treatment
article

Logarithmically transformed lactate-to-hemoglobin ratio demonstrates a threshold effect on 28-day mortality in sepsis: Analysis of the MIMIC-IV database

Shirong Lin, Xiuqin Zheng, Hongping Chen, Da Ke, Haiyang Song
article en

Abstract

Ln_LHR may represent a promising, readily available prognostic biomarker for sepsis mortality risk stratification, with a clinically meaningful threshold effect. This composite marker integrates critical pathophysiological information and may enhance risk assessment and guide clinical decision-making in sepsis management.

PLoS ONEVol. 21(2)
Fujian Medical University (CN), Fujian Provincial Hospital (CN), Fuzhou University (CN)
Good health and well-being
Openalex Percentile: Top 42%
Sepsis Diagnosis and Treatment
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