Logarithmically transformed lactate-to-hemoglobin ratio demonstrates a threshold effect on 28-day mortality in sepsis: Analysis of the MIMIC-IV database
Ln_LHR may represent a promising, readily available prognostic biomarker for sepsis mortality risk stratification, with a clinically meaningful threshold effect. This composite marker integrates critical pathophysiological information and may enhance risk assessment and guide clinical decision-making in sepsis management.
Authors
- Shirong Lin (ORCID: https://orcid.org/0000-0001-9959-482X)
- Xiuqin Zheng
- Hongping Chen (ORCID: https://orcid.org/0000-0002-1670-5449)
- Da Ke
- Haiyang Song
Institutions
- Fujian Medical University (CN)
- Fujian Provincial Hospital (CN)
- Fuzhou University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-02-26
- DOI
- https://doi.org/10.1371/journal.pone.0342994
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00