A case report of primary malignant melanoma of the cervix

Primary malignant melanoma of the cervix is an extremely rare malignant tumor, accounting for less than 0.5% of all cervical malignancies [1]. This article reports a case of a 66-year-old female patient who presented with "vaginal bleeding" and was diagnosed with primary malignant melanoma of the cervix via colposcopic biopsy and immunohistochemistry. The patient received dacarbazine chemotherapy. Through a systematic review of previous literature, this paper summarizes the clinicopathological features, diagnostic criteria, treatment strategies, and prognostic factors of this disease.

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Publication Details

Journal
Current Problems in Cancer Case Reports
Published
2026-02-26
DOI
https://doi.org/10.1016/j.cpccr.2026.100412
Primary Topic
Cutaneous Melanoma Detection and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

A case report of primary malignant melanoma of the cervix

Demei Ma, Yongxia Yang, Ya Liu, Ping Zhang
Current Problems in Cancer Case Reports
Cutaneous Melanoma Detection and Management
article

A case report of primary malignant melanoma of the cervix

Demei Ma, Yongxia Yang, Ya Liu, Ping Zhang
article en

Abstract

Primary malignant melanoma of the cervix is an extremely rare malignant tumor, accounting for less than 0.5% of all cervical malignancies [1]. This article reports a case of a 66-year-old female patient who presented with "vaginal bleeding" and was diagnosed with primary malignant melanoma of the cervix via colposcopic biopsy and immunohistochemistry. The patient received dacarbazine chemotherapy. Through a systematic review of previous literature, this paper summarizes the clinicopathological features, diagnostic criteria, treatment strategies, and prognostic factors of this disease.

Current Problems in Cancer Case ReportsVol. 21
Second Hospital of Shandong University (CN)
Openalex Percentile: Top 41%
Cutaneous Melanoma Detection and Management
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