Case report of extramedullary plasmacytoma within the left palatine tonsil in a 31-year-old female patient

Extramedullary plasmacytoma (EMP) is an uncommon variant (rare presentation) of plasma-cell neoplasia characterized by the proliferation of clonal plasma cells outside the bone marrow microenvironment. EMP most frequently arises in the head and neck region, particularly within soft-tissue structures of the upper aerodigestive tract. Herein, we present a case report of a 31-year-old patient diagnosed with a localized extramedullary plasmacytoma (EMP) of the left palatine tonsil at the University Hospital in Krakow. We are also presenting a summary of the EMP of the tonsil case reports from the PubMed database. This article aims to present a clinical case of extramedullary plasmacytoma involving the palatine tonsil in a 31-year-old woman, with a detailed description of the diagnostic process and therapeutic management. In addition, the article reviews alternative diagnostic approaches and treatment modalities reported in the literature.

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Publication Details

Journal
Polski Merkuriusz Lekarski
Published
2026-02-15
DOI
https://doi.org/10.36740/merkur202601114
Primary Topic
Multiple Myeloma Research and Treatments
Type
article
Field-Weighted Citation Impact
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article

Case report of extramedullary plasmacytoma within the left palatine tonsil in a 31-year-old female patient

Marcin Sobociński, Wiktoria Sobocińska, Gabriela Kubicka, Łukasz Kołodyński
Polski Merkuriusz Lekarski
Multiple Myeloma Research and Treatments
article

Case report of extramedullary plasmacytoma within the left palatine tonsil in a 31-year-old female patient

Marcin Sobociński, Wiktoria Sobocińska, Gabriela Kubicka, Łukasz Kołodyński
article en

Abstract

Extramedullary plasmacytoma (EMP) is an uncommon variant (rare presentation) of plasma-cell neoplasia characterized by the proliferation of clonal plasma cells outside the bone marrow microenvironment. EMP most frequently arises in the head and neck region, particularly within soft-tissue structures of the upper aerodigestive tract. Herein, we present a case report of a 31-year-old patient diagnosed with a localized extramedullary plasmacytoma (EMP) of the left palatine tonsil at the University Hospital in Krakow. We are also presenting a summary of the EMP of the tonsil case reports from the PubMed database. This article aims to present a clinical case of extramedullary plasmacytoma involving the palatine tonsil in a 31-year-old woman, with a detailed description of the diagnostic process and therapeutic management. In addition, the article reviews alternative diagnostic approaches and treatment modalities reported in the literature.

Polski Merkuriusz LekarskiVol. 54(1)
Jagiellonian University (PL), Cracow University of Technology (PL)
Gender equality, Good health and well-being
Openalex Percentile: Top 42%
Multiple Myeloma Research and Treatments
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