Untargeted LC–MS/MS Metabolomics Reveals Nrf2-Mediated Antioxidant Activation and Metabolic Reprogramming by IAA-Based Hydrazone Derivatives in Subchronic Cadmium Toxicity

These findings demonstrate that IAA-based hydrazone derivatives MBIH and FBIH afford superior protection against Cd-induced multi organ injury compared to ascorbic acid.

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Publication Details

Journal
Metabolites
Published
2026-02-26
DOI
https://doi.org/10.3390/metabo16030155
Primary Topic
Heavy Metal Exposure and Toxicity
Type
article
Field-Weighted Citation Impact
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article

Untargeted LC–MS/MS Metabolomics Reveals Nrf2-Mediated Antioxidant Activation and Metabolic Reprogramming by IAA-Based Hydrazone Derivatives in Subchronic Cadmium Toxicity

Sehar Madni, Muhammad Usama Munir, Kanwal Rehman, Muhammad Sajid Hamid Akash et al.
Metabolites
Heavy Metal Exposure and Toxicity
article

Untargeted LC–MS/MS Metabolomics Reveals Nrf2-Mediated Antioxidant Activation and Metabolic Reprogramming by IAA-Based Hydrazone Derivatives in Subchronic Cadmium Toxicity

Sehar Madni, Muhammad Usama Munir, Kanwal Rehman, Muhammad Sajid Hamid Akash, Aisha Rafique
article en

Abstract

These findings demonstrate that IAA-based hydrazone derivatives MBIH and FBIH afford superior protection against Cd-induced multi organ injury compared to ascorbic acid.

MetabolitesVol. 16(3)
Government College University, Faisalabad (PK), The Women University Multan (PK)
Openalex Percentile: Top 47%
Heavy Metal Exposure and Toxicity
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