Programmed cell death and risk of diabetic retinopathy: a Mendelian randomization study
This MR study supports the causal involvement of PCD in DR and identifies candidate genes (CTSH, IREB2, PGAM5, NQO1, TRIB3, and TNF) for therapeutic targeting or biomarker development in DR prevention or diagnosis.
Authors
- Huiying Lin
- Yufen Tan
- Yingying Chen (ORCID: https://orcid.org/0000-0003-0817-7612)
- Hengguang Wei
- Rupeng Zhao
- Hanyi Xu
- Na Li
Institutions
- Fujian Medical University (CN)
- Guangxi University (CN)
- Guangxi Medical University (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
- Union Hospital (CN)
- State Key Laboratory For Conservation and Utilization of Subtropical Agro-Bioresources (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2026-02-26
- DOI
- https://doi.org/10.1186/s12967-026-07921-9
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00