Establishing a Mouse Model of Vaginal Group B <i>Streptococcus</i> Infection

Source: Patras, K. A., Doran, K. S. A Murine Model of Group B Streptococcus Vaginal Colonization. J. Vis. Exp. (2016)This video demonstrates the preparation and vaginal inoculation of a hormone-treated female mouse with Group B Streptococcus to model infection. It explains how to culture and prepare the bacteria, administer the inoculum into the vaginal lumen, and ensure successful infection.

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Publication Details

Journal
Journal of Visualized Experiments
Published
2026-02-26
DOI
https://doi.org/10.3791/24425
Primary Topic
Neonatal and Maternal Infections
Type
article
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article

Establishing a Mouse Model of Vaginal Group B Streptococcus Infection

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Journal of Visualized Experiments
Neonatal and Maternal Infections
article

Establishing a Mouse Model of Vaginal Group B Streptococcus Infection

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Abstract

Source: Patras, K. A., Doran, K. S. A Murine Model of Group B Streptococcus Vaginal Colonization. J. Vis. Exp. (2016)This video demonstrates the preparation and vaginal inoculation of a hormone-treated female mouse with Group B Streptococcus to model infection. It explains how to culture and prepare the bacteria, administer the inoculum into the vaginal lumen, and ensure successful infection.

Journal of Visualized Experiments
Openalex Percentile: Top 45%
Neonatal and Maternal Infections
DOISourceOpenAlex
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