Time- and dose-dependent regulation of circular RNAs in the response of triple-negative breast cancer cells to ionizing radiation

The cell line-specific radiation-dependent circRNA expression patterns reflect the molecular diversity of TNBC, and pathway enrichments indicate the potential applications of these circRNAs as radiation sensitivity biomarkers and therapeutic targets to improve TNBC treatment efficacy.

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Publication Details

Journal
Clinical & Translational Oncology
Published
2026-02-26
DOI
https://doi.org/10.1007/s12094-026-04280-1
Primary Topic
Circular RNAs in diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Time- and dose-dependent regulation of circular RNAs in the response of triple-negative breast cancer cells to ionizing radiation

Maria Papatsirou, Eleni Mavrogonatou, Christos K. Kontos, Andreas Scorilas et al.
Clinical & Translational Oncology
Circular RNAs in diseases
article

Time- and dose-dependent regulation of circular RNAs in the response of triple-negative breast cancer cells to ionizing radiation

Maria Papatsirou, Eleni Mavrogonatou, Christos K. Kontos, Andreas Scorilas, Dimitris Kletsas
article en

Abstract

The cell line-specific radiation-dependent circRNA expression patterns reflect the molecular diversity of TNBC, and pathway enrichments indicate the potential applications of these circRNAs as radiation sensitivity biomarkers and therapeutic targets to improve TNBC treatment efficacy.

Clinical & Translational Oncology
National and Kapodistrian University of Athens (GR), National Centre of Scientific Research "Demokritos" (GR)
Good health and well-being
Openalex Percentile: Top 41%
Circular RNAs in diseases
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