<scp>TWEAK</scp> /Fn14 signaling drives oxidative cardiac injury in systemic lupus erythematosus: Evidence from patient biomarker studies, lupus mouse models, and cardiomyocyte assays
TWEAK/Fn14 signaling drives oxidative stress- mediated cardiomyocyte injury in SLE and represents a promising biomarker and therapeutic target for lupus-associated cardiac damage.
Authors
- Kaixuan Ren
- Yale Liu (ORCID: https://orcid.org/0000-0003-3936-1834)
- Xinyi Guo (ORCID: https://orcid.org/0009-0005-3428-9396)
- Juan Wang (ORCID: https://orcid.org/0000-0003-0767-5687)
- Yan Zhu
- Mingzhu Zhou (ORCID: https://orcid.org/0009-0004-8679-7360)
- Yumin Xia
- Xueting Peng
- Dan Zhang
- Huanhuan Huo
- Yan Zhang
- Meixuan Li
- Xiaoqian Hu
Institutions
- Vanderbilt University (US)
- Northwest University (CN)
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
- Xijing Hospital (CN)
- First Hospital of Xi'an (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Arthritis & Rheumatology
- Published
- 2026-02-26
- DOI
- https://doi.org/10.1002/art.70110
- Primary Topic
- NF-κB Signaling Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00