Double trouble: a rare case of quadricuspid aortic valve and anomalous right coronary artery

guideline-supported stress testing in risk stratification and avoidance of unnecessary intervention [3] Fig. 1.A 44-year-old male with high functional capacity presented with mid-sternal discomfort.Coronary CT angiography (CCTA) revealed an anomalous right coronary artery (RCA) from the left coronary cusp (Fig. 1, Panel A-B) and a quadricuspid aortic valve (QAV) (Fig. 1, Panel C).The RCA followed an interarterial course with a slit-like ostium (5.0 1.8 mm), acute takeoff angle, and 5.0 mm intramural segment [1].CT-derived fractional flow reserve (FFRct) was preserved (0.95) (Panel D), concordant with normal SPECT and absence of ischemia.Although FFRct is validated mainly in atherosclerosis and may not detect dynamic compression in anomalous aortic origin, concordant normal findings supported low ischemic risk.Cardiac magnetic resonance showed mild-to-moderate aortic regurgitation (regurgitant volume 19 mL, fraction 22%), without ventricular dilation (Fig. 1, Panel E-F).Associations between aortic valve dysplasia and anomalous coronary origin have been described [2], though quadricuspid morphology remains rare.This case highlights the complementary role of CCTA, FFRct, and

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Journal
The International Journal of Cardiovascular Imaging
Published
2026-02-26
DOI
https://doi.org/10.1007/s10554-026-03669-x
Primary Topic
Coronary Artery Anomalies
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article
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article

Double trouble: a rare case of quadricuspid aortic valve and anomalous right coronary artery

Malek Nayfeh, Bruno Bezerra Lima, Tuna Ustunkaya, Aamuktha R. Karla
The International Journal of Cardiovascular Imaging
Coronary Artery Anomalies
article

Double trouble: a rare case of quadricuspid aortic valve and anomalous right coronary artery

Malek Nayfeh, Bruno Bezerra Lima, Tuna Ustunkaya, Aamuktha R. Karla
article en

Abstract

guideline-supported stress testing in risk stratification and avoidance of unnecessary intervention [3] Fig. 1.A 44-year-old male with high functional capacity presented with mid-sternal discomfort.Coronary CT angiography (CCTA) revealed an anomalous right coronary artery (RCA) from the left coronary cusp (Fig. 1, Panel A-B) and a quadricuspid aortic valve (QAV) (Fig. 1, Panel C).The RCA followed an interarterial course with a slit-like ostium (5.0 1.8 mm), acute takeoff angle, and 5.0 mm intramural segment [1].CT-derived fractional flow reserve (FFRct) was preserved (0.95) (Panel D), concordant with normal SPECT and absence of ischemia.Although FFRct is validated mainly in atherosclerosis and may not detect dynamic compression in anomalous aortic origin, concordant normal findings supported low ischemic risk.Cardiac magnetic resonance showed mild-to-moderate aortic regurgitation (regurgitant volume 19 mL, fraction 22%), without ventricular dilation (Fig. 1, Panel E-F).Associations between aortic valve dysplasia and anomalous coronary origin have been described [2], though quadricuspid morphology remains rare.This case highlights the complementary role of CCTA, FFRct, and

The International Journal of Cardiovascular Imaging
University of Tennessee at Chattanooga (US), Vanderbilt University (US), Erlanger Health System (US), Vanderbilt University Medical Center (US)
Good health and well-being
Openalex Percentile: Top 42%
Coronary Artery Anomalies
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