Effectiveness of Doxycycline in Combination With Other Antibiotics for Gram-Positive Periprosthetic Joint Infections: A Causal Inference Study
Doxycycline in combination with other antibiotics was not associated with 12-month treatment failure in PJI caused by <i>Staphylococcus</i>, <i>Corynebacterium</i>, or <i>Cutibacterium,</i> with potential benefits in <i>S. aureus</i> infection warranting confirmation in prospective studies.
Authors
- Amadou-Khalilou Sow (ORCID: https://orcid.org/0000-0001-8073-9128)
- Ludovic Labattut (ORCID: https://orcid.org/0000-0003-1643-8974)
- Christine Binquet (ORCID: https://orcid.org/0000-0002-9417-5754)
- Coralie Humann
- Thibault Sixt (ORCID: https://orcid.org/0000-0002-2966-6346)
- Alice Bordet (ORCID: https://orcid.org/0000-0003-1598-8480)
- Jeanne Godon
- Valentin Pineau
- Lucie Amoureux (ORCID: https://orcid.org/0000-0003-0763-0921)
- S. Das Neves
- Mathieu Blot
- Sophie Mahy
- Lionel Piroth
Institutions
- Université de Bourgogne (FR)
- Centre Hospitalier Universitaire de Nantes (FR)
- CHU Dijon Bourgogne (FR)
- ENSA Dijon (FR)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2026-02-22
- DOI
- https://doi.org/10.1093/ofid/ofag098
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00