Neutrophils have altered response to acute respiratory viral infection in sputum of patients with rheumatoid arthritis
Immune cell proportions in donors with RA and in healthy donors are similar both before and after infection. However, transcriptional differences within lung neutrophils persist up to 30 days following respiratory infection.
Authors
- CATE SPEAKE
- Matthew Lawrance
- Hannah A. DeBerg (ORCID: https://orcid.org/0000-0002-5263-158X)
- Anne Chaize
- Holly M. Akilesh (ORCID: https://orcid.org/0000-0003-0015-6788)
- Carmen R. Mikacenic (ORCID: https://orcid.org/0000-0001-8966-5161)
- Stephan Pribitzer (ORCID: https://orcid.org/0000-0003-4124-0484)
- Adarsh Manjunath
- Naresh Doni Jayavelu
- Jane H. Buckner
- Gabrielle Z. Yize Smith-Rockne
- Matthew C. Altman
- Vivian Gersuk
Institutions
- University of Washington (US)
- Benaroya Research Institute
Publication Details
- Journal
- Journal of Allergy and Clinical Immunology Global
- Published
- 2026-02-27
- DOI
- https://doi.org/10.1016/j.jacig.2026.100665
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00