Rethinking anorexia nervosa through the lens of control, compulsion and reward: Neurobiological insights into addiction-like features via the dopaminergic, endocannabinoid, and orexinergic systems − A narrative review
AN may be conceptualized at the intersection of addiction and compulsivity, with starvation-induced reward processes and habitual restriction contributing to illness persistence. Based on the reviewed evidence, we hypothesize a Starvation-Drive Model of Addiction-Like Features in AN.
Authors
- Grażyna Biała (ORCID: https://orcid.org/0000-0001-8270-9635)
- Wojciech Ziemichód (ORCID: https://orcid.org/0000-0002-4980-3926)
- Natalia Kajka (ORCID: https://orcid.org/0000-0002-1781-6773)
- Aleksandra Metelska (ORCID: https://orcid.org/0000-0002-3166-1296)
- Zuzanna Rząd (ORCID: https://orcid.org/0000-0002-5034-3410)
- Hanna Karakuła-Juchnowicz
- Karolina Grabowska
Institutions
- Medical University of Lublin (PL)
- Medical University of Silesia (PL)
- University of Silesia in Katowice (PL)
Publication Details
- Journal
- Neuroscience & Biobehavioral Reviews
- Published
- 2026-02-26
- DOI
- https://doi.org/10.1016/j.neubiorev.2026.106615
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00