Revisiting the TSH range in older adults: associations between subclinical hypothyroidism and geriatric conditions

Age-related TSH elevation is common among older adults. Mild SCH was not linked to geriatric conditions, whereas moderate-to-severe SCH showed associations with cerebral microbleeds and sarcopenia. Given the limited number of participants in this category, these findings should be interpreted cautiously and require confirmation in longitudinal studies.

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Publication Details

Journal
Journal of the Endocrine Society
Published
2026-02-23
DOI
https://doi.org/10.1210/jendso/bvag045
Primary Topic
Thyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Revisiting the TSH range in older adults: associations between subclinical hypothyroidism and geriatric conditions

Toshiki Kogai, R. Kawamori, Saori Kakehi, Toyoyoshi Uchida et al.
Journal of the Endocrine Society
Thyroid Disorders and Treatments
article

Revisiting the TSH range in older adults: associations between subclinical hypothyroidism and geriatric conditions

Toshiki Kogai, R. Kawamori, Saori Kakehi, Toyoyoshi Uchida, T. Tajima, H Watada, Hiroki Tabata, Hitoshi Naito, Yuya Nishida, Yoshifumi Tamura, Hideyoshi Kaga, Yuki Someya, Satoshi Kadowaki, Naoaki Ito
article en

Abstract

Age-related TSH elevation is common among older adults. Mild SCH was not linked to geriatric conditions, whereas moderate-to-severe SCH showed associations with cerebral microbleeds and sarcopenia. Given the limited number of participants in this category, these findings should be interpreted cautiously and require confirmation in longitudinal studies.

Journal of the Endocrine SocietyVol. 10(4)
Juntendo University (JP)
Openalex Percentile: Top 43%
Thyroid Disorders and Treatments
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