Preliminary in-vivo evaluation of [68Ga]Ga-FAPI-46 in a fibroblast activation protein–negative breast cancer model
[68Ga]Ga-FAPI-46 showed efficient radiolabelling with high RCP and short-term stability. Its low accumulation in FAP-negative tumours supports tracer selectivity and provides a baseline for comparative studies in FAP-expressing tumour models.
Authors
- Hairil Rashmizal Abdul Razak (ORCID: https://orcid.org/0000-0002-8266-0381)
- Anee Suryani Sued
- Siti Muhamad
- Mohd Faiz Mustaffa (ORCID: https://orcid.org/0000-0001-7785-4774)
- Wan Hamirul Bahrin Wan Kamal (ORCID: https://orcid.org/0000-0001-7990-4034)
- Muhamad Faiz Othman
- Hishar Hassan
- Nur Nadhira Jafperi
- Saifullizan Mohamad
- Nazreen Waeleh
Institutions
- Universiti Putra Malaysia (MY)
- University of Exeter (GB)
- Malaysian Nuclear Agency (MY)
- Technical University of Malaysia Malacca (MY)
- Universiti Teknologi MARA (MY)
Publication Details
- Journal
- Nuclear Medicine Communications
- Published
- 2026-02-26
- DOI
- https://doi.org/10.1097/mnm.0000000000002131
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00