NOX2 exacerbates periodontitis via JAK2-STAT3-mediated ferroptosis of gingival epithelial cells
NOX2 activation promoted periodontitis by driving ferroptosis via the ROS/JAK2-STAT3 pathway, highlighting its potential as a novel therapeutic target.
Authors
- Wei Wang (ORCID: https://orcid.org/0000-0002-1135-8265)
- Lei Li (ORCID: https://orcid.org/0000-0001-8723-3461)
- Xiaonan Zhang
- Yujuan He
- Zimeng Wang
- Bo Yang
- Yuan Ping
Institutions
- Ministry of Education (TH)
- Chongqing Medical and Pharmaceutical College (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-26
- DOI
- https://doi.org/10.3389/fimmu.2026.1744612
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00