Prospective Biomarkers of SARS-CoV-2 Vaccine Seroconversion in Patients with Haematological Malignancies

These results suggest that HM patients have impaired T-cell immunity, and non-responders may be identified by low levels of serum CXCL13 and CRTAM. This allows for the identification of at-risk patients who would benefit from alternative COVID-19 prophylaxis strategies.

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Publication Details

Journal
Vaccines
Published
2026-02-25
DOI
https://doi.org/10.3390/vaccines14030201
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Prospective Biomarkers of SARS-CoV-2 Vaccine Seroconversion in Patients with Haematological Malignancies

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Vaccines
SARS-CoV-2 and COVID-19 Research
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Prospective Biomarkers of SARS-CoV-2 Vaccine Seroconversion in Patients with Haematological Malignancies

Michelle M. Spanevello, Pauline Crooks, Kirk Morris, Smith Rjh, Andrea S. Henden, Katie E. Lineburg, K. Guppy-Coles, Justine Leach, Jyothy Raju, Siok-Keen Tey, Louise Ng, Annabel Waugh, Sophie C. Hamann, Laetitia Le Texier, Christine Bristow
article en

Abstract

These results suggest that HM patients have impaired T-cell immunity, and non-responders may be identified by low levels of serum CXCL13 and CRTAM. This allows for the identification of at-risk patients who would benefit from alternative COVID-19 prophylaxis strategies.

VaccinesVol. 14(3)
The University of Queensland (AU), QIMR Berghofer Medical Research Institute (AU), Royal Brisbane and Women's Hospital (AU)
QIMR Berghofer Medical Research Institute, Australian Government, Metro North Hospital and Health Service
Good health and well-being
Openalex Percentile: Top 42%
SARS-CoV-2 and COVID-19 Research
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