Sequential Amiodarone‐Induced Thyroid Dysfunction: From Myxedema Coma to Late‐Onset Type 1 Thyrotoxicosis After Drug Withdrawal

Our report underscores three key points: (1) the prolonged metabolic effects of iodine load and tissue toxicity even after amiodarone cessation, (2) the possibility of reversible amiodarone-induced hypothyroidism preceding subsequent thyrotoxicosis, and (3) the need for long-term thyroid function monitoring, even after amiodarone withdrawal.

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Publication Details

Journal
Clinical Case Reports
Published
2026-02-23
DOI
https://doi.org/10.1002/ccr3.72158
Citations
1
Primary Topic
Thyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
30.73
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article

Sequential Amiodarone‐Induced Thyroid Dysfunction: From Myxedema Coma to Late‐Onset Type 1 Thyrotoxicosis After Drug Withdrawal

D E Soares, Lia Ferreira
1 citations
Clinical Case Reports
Thyroid Disorders and Treatments
30.73
article

Sequential Amiodarone‐Induced Thyroid Dysfunction: From Myxedema Coma to Late‐Onset Type 1 Thyrotoxicosis After Drug Withdrawal

D E Soares, Lia Ferreira
article en
1 citations

Abstract

Our report underscores three key points: (1) the prolonged metabolic effects of iodine load and tissue toxicity even after amiodarone cessation, (2) the possibility of reversible amiodarone-induced hypothyroidism preceding subsequent thyrotoxicosis, and (3) the need for long-term thyroid function monitoring, even after amiodarone withdrawal.

Clinical Case ReportsVol. 14(3)
Administração Regional de Saúde de Lisboa e Vale do Tejo (PT), Hospital de Santo António (PT)
Good health and well-being
Openalex Percentile: Top 1%
Thyroid Disorders and Treatments
30.73
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