The Psycho-Social Impact of Dental Emergencies in COVID-19 Patients: A Cross-Sectional Case–Control Study

<b>Background:</b> The COVID-19 pandemic severely restricted access to routine dental care, resulting in delayed treatment and increased presentation of dental emergencies. When combined with SARS-CoV-2 infection, these conditions may significantly impair psycho-social well-being and quality of life (QoL). This study assessed the impact of dental emergencies on QoL in patients with COVID-19. <b>Methods:</b> A cross-sectional case-control study was conducted between January 2022 and April 2024, including 240 adult patients with confirmed COVID-19. The case group comprised 60 patients presenting with dental emergencies, while the control group included 180 COVID-19 patients without emergency dental needs. Quality of life was evaluated using the 32-item Quality-of-Life Inventory (QOLI), yielding a continuous global score (SBQ) and an ordinal quality-of-life category (CGV). Group comparisons were performed using Welch's <i>t</i>-test and logistic regression, with effect sizes and 95% confidence intervals reported. Multivariable analyses were adjusted for age and sex. <b>Results:</b> Patients with dental emergencies reported markedly poorer global QoL compared to controls (mean SBQ difference = -2.04 points; Cohen's d = -1.50; <i>p</i> < 0.001). The presence of a dental emergency was strongly associated with severe QoL impairment, with emergency patients showing substantially higher odds of unfavorable CGV categories (adjusted OR ≈ 20.4; 95% CI: 8.6-48.5; <i>p</i> < 0.001). These associations remained robust after adjustment for demographic covariates. <b>Conclusions:</b> Dental emergencies in patients with COVID-19 are associated with a profound deterioration in quality of life. Ensuring timely access to emergency dental services during public health crises may substantially reduce psycho-social burden and improve patient-centered outcomes.