Linear and Nonlinear Associations Between Lipoprotein(a) and the Risks of Atherosclerotic Cardiovascular Disease

Elevated Lp(a) concentrations were causally associated with ASCVD risk, showing a predominantly graded relationship with possible nonlinearity at very high levels, supporting routine Lp(a) measurement and the development of Lp(a)-lowering therapies.

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Publication Details

Journal
Circulation Journal
Published
2026-02-26
DOI
https://doi.org/10.1253/circj.cj-25-0847
Citations
1
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
Field-Weighted Citation Impact
39.15
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article

Linear and Nonlinear Associations Between Lipoprotein(a) and the Risks of Atherosclerotic Cardiovascular Disease

Hwang LC, Chih-Jun Lai, Tsai Mc, Hsien-Yu Fan et al.
1 citations
Circulation Journal
Lipoproteins and Cardiovascular Health
39.15
article

Linear and Nonlinear Associations Between Lipoprotein(a) and the Risks of Atherosclerotic Cardiovascular Disease

Hwang LC, Chih-Jun Lai, Tsai Mc, Hsien-Yu Fan, Kuo-Liong Chien
article en
1 citations

Abstract

Elevated Lp(a) concentrations were causally associated with ASCVD risk, showing a predominantly graded relationship with possible nonlinearity at very high levels, supporting routine Lp(a) measurement and the development of Lp(a)-lowering therapies.

Circulation Journal
National Taiwan University (TW), Mackay Memorial Hospital (TW), Mackay Medical University (TW), National Taiwan University Hospital (TW), Taipei Medical University (TW)
Good health and well-being
Openalex Percentile: Top 1%
Lipoproteins and Cardiovascular Health
39.15
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