Intravital single-molecule imaging reveals cytoskeletal turnover as a driver of membrane remodeling in live animals
Intravital single-molecule microscopy enables direct measurement of molecular kinetics underlying dynamic cellular behaviors in intact living organs.
Authors
- Melissa R. Mikolaj (ORCID: https://orcid.org/0000-0002-5452-1683)
- Marco Heydecker (ORCID: https://orcid.org/0009-0006-8409-7058)
- Tobias Meckel (ORCID: https://orcid.org/0000-0003-0759-2072)
- Harshad D. Vishwasrao
- Desu Chen (ORCID: https://orcid.org/0000-0003-4255-0361)
- Jiji Chen (ORCID: https://orcid.org/0009-0005-8846-7610)
- Edna Hardeman
- Andrius Masedunskas
- Kedar Narayan
- Peter Gunning
Institutions
- National Institutes of Health (US)
- Technische Universität Darmstadt (DE)
- UNSW Sydney (AU)
- National Institute of Biomedical Imaging and Bioengineering (US)
- Frederick National Laboratory for Cancer Research (US)
- National Cancer Institute (US)
- Center for Cancer Research (US)
Publication Details
- Journal
- bioRxiv (Cold Spring Harbor Laboratory)
- Published
- 2026-02-25
- DOI
- https://doi.org/10.64898/2026.02.25.708035
- Primary Topic
- Cellular transport and secretion
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Health and Human Services
- University of New South Wales
- National Institutes of Health
- Medical Research Council
- National Health and Medical Research Council
- National Cancer Institute