Prevalence of <i>Plasmodium falciparum</i> histidine rich protein 2/3 gene deletions affecting rapid diagnostic test performance in travellers
In this traveller cohort, pfhrp2/3 deletions occurred in 4 of 115 (3.5%) patients, with no double deletions observed. Notably, 51.3% of patients had visited countries anticipated to surpass the WHO 5% pfhrp2/3 threshold by 2028. Continued monitoring of pfhrp2/3 deletions in non-endemic settings is needed to guide testing strategies.
Authors
- Matthias Weiss-Tessbach (ORCID: https://orcid.org/0000-0003-0131-9091)
- Renate Schneider
- Julia Walochnik (ORCID: https://orcid.org/0000-0003-0356-2853)
- Lorenz Schubert (ORCID: https://orcid.org/0000-0001-9181-8614)
- Felix Lötsch (ORCID: https://orcid.org/0000-0002-6938-9523)
- Stefan Winkler
- Olivia Detzlhofer
- Jessica Kirchner
Institutions
- St Anna Children's Hospital (AT)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Journal of Travel Medicine
- Published
- 2026-02-21
- DOI
- https://doi.org/10.1093/jtm/taag007
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00