Associations of body fat percentage with C-reactive protein levels in Canadian adults with and without osteoarthritis: Findings from the Canadian Longitudinal Study on Aging (CLSA)
There were small but meaningful associations between CRP and each of percent adiposity and appendicular lean mass index. These associations were present regardless of OA and multimorbidity status. Percent adiposity, but not OA status, was consistently associated with systemic inflammation, suggesting that adiposity driven inflammation may contribute to OA related health outcomes.
Authors
- Chopp-Hurley JN
- Emily G. Wiebenga
- M. E. Bowdish Dawn
- Paul W. Stratford (ORCID: https://orcid.org/0000-0003-4971-2386)
- Chris P. Verschoor (ORCID: https://orcid.org/0000-0001-6190-2655)
- Marina Mourtzakis (ORCID: https://orcid.org/0000-0001-7350-0151)
- Kendal A. Marriott
- Monica R. Maly
Institutions
- University of Waterloo (CA)
- York University (CA)
- Health Sciences North (CA)
- McMaster University (CA)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-02-26
- DOI
- https://doi.org/10.1371/journal.pone.0341604
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Government of Canada
- Arthritis Society
- University of Waterloo
- Canadian Institutes of Health Research
- Institute of Musculoskeletal Health and Arthritis