Extracellular vesicles delivering TIMP-2 modulate MMP-1, MMP-2, and MMP-9 expression in human lung adenocarcinoma A549 cells
Our findings suggest a rational approach for exploring EV-based gene transfer targeting MMPs in lung cancer.
Authors
- Agata Kowalczyk (ORCID: https://orcid.org/0000-0002-1911-8311)
- Alicja Targońska (ORCID: https://orcid.org/0000-0002-8939-1743)
- Żaneta Słyk (ORCID: https://orcid.org/0000-0002-1178-7908)
- Agnieszka Stawarska (ORCID: https://orcid.org/0000-0001-9345-1254)
- Ireneusz P. Grudziński (ORCID: https://orcid.org/0000-0002-6113-1771)
- Anna Maria Nowicka
- Magdalena Bamburowicz-Klimkowska
- Maciej Małecki
Institutions
- Medical University of Warsaw (PL)
- University of Warsaw (PL)
- Polish Academy of Sciences (PL)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-02-26
- DOI
- https://doi.org/10.3389/fphar.2026.1784404
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00