Genomic Profiling of Antibody Repertoire in Rongchang Pigs Uncovers Conserved V(D)J Gene Usage and Breed-Specific Diversification

These results clarify the conserved and breed-specific characteristics of RC pig antibody repertoires, establishing a basis for exploring the genetic regulation of V(D)J-mediated antibody repertoire changes under varied immune conditions. This work also provides genomic support for the rational utilization of RC pig genetic resources.

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Publication Details

Journal
Genes
Published
2026-02-26
DOI
https://doi.org/10.3390/genes17030262
Primary Topic
Xenotransplantation and immune response
Type
article
Field-Weighted Citation Impact
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article

Genomic Profiling of Antibody Repertoire in Rongchang Pigs Uncovers Conserved V(D)J Gene Usage and Breed-Specific Diversification

Xueqin Amy Liu, Xinyu Wu, Qiao Li, Chenchen Ding et al.
Genes
Xenotransplantation and immune response
article

Genomic Profiling of Antibody Repertoire in Rongchang Pigs Uncovers Conserved V(D)J Gene Usage and Breed-Specific Diversification

Xueqin Amy Liu, Xinyu Wu, Qiao Li, Chenchen Ding, Liangpeng Ge, Jing Sun, Meng Wu, Hailin Zhang
article en

Abstract

These results clarify the conserved and breed-specific characteristics of RC pig antibody repertoires, establishing a basis for exploring the genetic regulation of V(D)J-mediated antibody repertoire changes under varied immune conditions. This work also provides genomic support for the rational utilization of RC pig genetic resources.

GenesVol. 17(3)
Chongqing Academy of Animal Science (CN), Chongqing University of Technology (CN)
Openalex Percentile: Top 43%
Xenotransplantation and immune response
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