Heart Rate Variability Discriminates Outcomes After Pediatric Cardiac Arrest

Lower mHRVi over the first 12 hours of PICU admission after cardiac arrest demonstrated moderate discrimination for 1-week in-hospital mortality and poor neurologic outcomes. These findings suggest that mHRVi may serve as a helpful adjunct within multimodal prognostication frameworks, though further validation in larger, diverse cohorts is required before clinical application.

Authors

Craig M. Smith (ORCID: https://orcid.org/0000-0002-2894-2433)
Duncan Mackie (ORCID: https://orcid.org/0000-0001-7744-7634)
Colleen M. Badke (ORCID: https://orcid.org/0000-0002-7822-1669)
L. Nelson Sanchez-Pinto

Institutions

Northwestern University (US)
Lurie Children's Hospital (US)

Publication Details

Journal: Pediatric Critical Care Medicine
Published: 2026-02-26
DOI: https://doi.org/10.1097/pcc.0000000000003904
Primary Topic: Heart Rate Variability and Autonomic Control
Type: article
Field-Weighted Citation Impact: 0.00

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article

Heart Rate Variability Discriminates Outcomes After Pediatric Cardiac Arrest

Craig M. Smith, Duncan Mackie, Colleen M. Badke, L. Nelson Sanchez-Pinto

Feb 26, 2026

Pediatric Critical Care Medicine

Heart Rate Variability and Autonomic Control

article

Heart Rate Variability Discriminates Outcomes After Pediatric Cardiac Arrest

Craig M. Smith, Duncan Mackie, Colleen M. Badke, L. Nelson Sanchez-Pinto

February 26, 2026article en

Abstract

Lower mHRVi over the first 12 hours of PICU admission after cardiac arrest demonstrated moderate discrimination for 1-week in-hospital mortality and poor neurologic outcomes. These findings suggest that mHRVi may serve as a helpful adjunct within multimodal prognostication frameworks, though further validation in larger, diverse cohorts is required before clinical application.

Pediatric Critical Care Medicine

Northwestern University (US), Lurie Children's Hospital (US)

Reduced inequalities

Openalex Percentile: Top 47%

Heart Rate Variability and Autonomic Control

DOI Source OpenAlex

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