Interplay of the nasal microbiome and epigenome among adolescents

Our findings support the hypothesis that the nasal microbiome is associated with small-to-modest variation in the nasal epigenome. Future research is needed to investigate how the relationship between the nasal microbiome and epigenome is impacted by environmental exposures, as well as the health effects of microbial and epigenetic variation in early life and across the life course.

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Publication Details

Journal
Clinical Epigenetics
Published
2026-02-27
DOI
https://doi.org/10.1186/s13148-026-02093-1
Primary Topic
Pediatric health and respiratory diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Interplay of the nasal microbiome and epigenome among adolescents

Javier Pérez-García, Andrés Felipe Millán Cardenas, Anne K. Bozack, Peggy S. Lai et al.
Clinical Epigenetics
Pediatric health and respiratory diseases
article

Interplay of the nasal microbiome and epigenome among adolescents

Javier Pérez-García, Andrés Felipe Millán Cardenas, Anne K. Bozack, Peggy S. Lai, Sheryl Rifas-Shiman, Emily Oken, Diane R. Gold, Brent Coull, Joanne Sordillo, Marie-France Hivert, Yanjiao Zhou, Jenny Jyoung Lee
article en

Abstract

Our findings support the hypothesis that the nasal microbiome is associated with small-to-modest variation in the nasal epigenome. Future research is needed to investigate how the relationship between the nasal microbiome and epigenome is impacted by environmental exposures, as well as the health effects of microbial and epigenetic variation in early life and across the life course.

Clinical Epigenetics
Brigham and Women's Hospital (US), Harvard University (US), Ewha Womans University (KR), VA Boston Healthcare System (US), Massachusetts General Hospital (US), Stanford Health Care (US), Harvard Pilgrim Health Care (US), Stanford Medicine (US), New York University (US), UConn Health (US), Stanford University (US)
Good health and well-being
Openalex Percentile: Top 49%
Pediatric health and respiratory diseases
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